Defy Medical wins on peptide breadth — they carry a wider advanced formulary including TB-500, Tesamorelin, and niche peptides. PeterMD wins on price transparency, affordability (TRT from $77/mo), scale (13,900+ Trustpilot reviews), and their unique longevity compounds (Metformin, Rapamycin). Choose Defy for peptide depth; choose PeterMD for cost-effective, broader longevity medicine.
| Defy Medical | PeterMD | |
|---|---|---|
| Monthly Cost Est. | ~$200/mo+ (not published) | $77–$211/mo (published by protocol) |
| Labs Required? | Yes | TRT yes (~$95); longevity protocols no |
| Est. Lab Cost | $100–$300/yr | $250/yr (TRT monitoring) |
| Consult Type | Video (1-hour physician) | Video — founded by Bryan Henry PhD |
| Sermorelin | Yes | $211/mo (1-mo), $399 (2-mo), $585 (3-mo) |
| NAD+ | Yes (~$180–$225/vial) | $125/mo caps, $210/60-day, $310/90-day |
| BPC-157 | Yes | Not offered |
| TB-500 / Tesamorelin | Yes | Not offered |
| Metformin / Rapamycin | Not offered | Yes — longevity focus |
| Glutathione | Not offered | Yes |
| TRT | Yes | From $77/mo annual |
| GLP-1 Weight Loss | Limited | Sema from $165/mo ongoing |
| Trustpilot | 4.2/5 (3,700+ reviews) | 4.8–5.0/5 (13,900+ reviews) |
| State Restrictions | No labs: NY/NJ/PA/RI/MA | Not in AL/ID; limited labs in 10+ states |
| Full Review | Read Review → | Read Review → |
PeterMD publishes clear pricing for every protocol on their website. NAD+ capsules start at $125/month, Sermorelin at $211/month, TRT as low as $77/month on annual plans, and Semaglutide at $270 for the first 2 months then $165/month ongoing. Initial TRT labs cost approximately $95. This level of transparency makes budgeting straightforward.
Defy Medical requires direct inquiry for all pricing. Their peptide vials are estimated at $180–$225 each, labs add $100–$300/yr, and consultation fees are billed separately. For cost-conscious patients who want to compare protocols before committing, PeterMD is far easier to evaluate.
Not published. Per-service. Labs $100–$300/yr. Vials ~$180–$225 each. Must contact clinic for quotes.
Published pricing. NAD+ $125/mo. Sermorelin $211/mo. TRT $77+/mo. GLP-1 $165/mo. Labs ~$95 for TRT.
Defy Medical wins on peptide depth. They carry TB-500, Tesamorelin, Kisspeptin, IGF-1 LR3, MOTS-C, Epithalon, AOD-9604, and more — a formulary that goes well beyond what most telehealth clinics offer.
PeterMD wins on longevity breadth. They offer Metformin, Rapamycin, and Glutathione — compounds that Defy Medical doesn't carry. For users pursuing longevity optimization beyond peptides and hormones, PeterMD's protocol menu is more relevant. Both offer Sermorelin and NAD+; Defy Medical's access to advanced peptides remains the key differentiator for that use case.
BPC-157, TB-500, CJC-1295/Ipa, Tesamorelin, Sermorelin, NAD+, AOD-9604, Epithalon, GHK-Cu, IGF-1 LR3, Kisspeptin, MOTS-C.
Sermorelin, NAD+, Glutathione, Metformin, Rapamycin, Enclomiphene, HCG, TRT, GLP-1, ED, hair loss, women's health.
If your protocol requires advanced peptides — TB-500, Tesamorelin, IGF-1 LR3, MOTS-C, or others — Defy Medical is the only choice between the two.
If you want transparent pricing, affordable access to Sermorelin, NAD+, TRT, or longevity compounds like Metformin and Rapamycin, PeterMD delivers better value with a significantly larger and more publicly accessible platform. For longevity-focused users, PeterMD's unique formulary is a meaningful differentiator.
Defy Medical for advanced peptide protocols — BPC-157, TB-500, Tesamorelin, Kisspeptin, IGF-1 LR3. PeterMD offers Sermorelin and NAD+ alongside a wider longevity formulary (Metformin, Rapamycin).
PeterMD is more affordable with published pricing. TRT starts at $77/mo, NAD+ at $125/mo, Sermorelin at $211/mo. Defy Medical doesn't publish pricing and total costs typically exceed $200/month plus labs.
Yes — PeterMD offers Metformin, Rapamycin, and Glutathione as part of their longevity protocol. Defy Medical does not carry these compounds.
PeterMD has 13,900+ Trustpilot reviews with a 4.8–5.0/5 rating, making them one of the most reviewed telehealth clinics in the hormone optimization space. Defy Medical has 3,700+ reviews at 4.2/5.