A telomere-extending tetrapeptide derived from pineal gland tissue, backed by over 40 years of Russian anti-aging research — one of the most studied longevity peptides available.
| Provider | Type | Price | Review | Link |
|---|---|---|---|---|
| Defy Medical | Telehealth | ~$200/mo | Read review | Get Started → |
| NextGenPeps | Research | $32 / 10mg | — | Visit Site → |
| Nationwide Peptides | Research | $52 / 10mg | — | Visit Site → |
Telehealth = physician-prescribed. Research = for research use only, no prescription required. Learn the difference →
Epithalon (also spelled Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on Epithalamin — a natural polypeptide isolated from bovine pineal gland extract by Professor Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology. Research on Epithalon spans over four decades and includes animal longevity studies, cell culture research, and human clinical trials — making it one of the most thoroughly studied anti-aging peptides available.
Epithalon's primary studied mechanism is the activation of telomerase — the enzyme responsible for maintaining and lengthening telomeres, the protective caps at the end of chromosomes. Telomere length is closely correlated with cellular age and longevity; shorter telomeres are associated with accelerated aging and age-related disease. In vitro and animal studies show Epithalon increases telomerase activity, extends telomere length, and prolongs the lifespan of human cells in culture.
Beyond telomere biology, Epithalon research has documented melatonin normalization (the pineal gland produces melatonin), antioxidant activity, DNA repair support, and modulation of neuroendocrine function. Human trials in elderly subjects showed improved sleep quality, normalized circadian rhythms, and general indicators of biological aging. Epithalon is typically used in 10–20 day cycles, repeated once or twice per year as part of a longevity protocol.
Use code 3LUIZH10 at NextGenPeps for a discount on Epithalon. Often stacked with Pinealon in longevity protocols.