The foundation of male hormone optimization — physician-prescribed testosterone replacement therapy is available through all major telehealth clinics and requires regular lab monitoring.
| Provider | Type | Price | Review | Link |
|---|---|---|---|---|
| Maximus | Telehealth | $199/mo | Read review | Get Started → |
| Marek Health | Telehealth | $166/mo | Read review | Get Started → |
| Limitless Alt Med | Telehealth | $115–$275/mo | Read review | Get Started → |
| PeterMD | Telehealth | $150/mo | Read review | Get Started → |
| Defy Medical | Telehealth | ~$200/mo | Read review | Get Started → |
| Tonik | Telehealth | $85/mo | Read review | Get Started → |
Testosterone requires a physician prescription — not available from research vendors. See full clinic comparison →
Testosterone replacement therapy (TRT) is the medical treatment of hypogonadism — clinically low testosterone levels — using exogenous testosterone. As testosterone naturally declines with age (approximately 1–2% per year after age 30), many men experience symptoms including low libido, erectile dysfunction, fatigue, loss of muscle mass, increased body fat, and mood changes. TRT addresses these symptoms by restoring testosterone to optimal physiological levels.
Exogenous testosterone is administered via subcutaneous or intramuscular injection, topical gel/cream, or pellet implant. Weekly or biweekly injections of testosterone cypionate or enanthate are the most common protocol in telehealth — they provide stable, predictable levels and are the most cost-effective option. The physician determines dosing based on baseline bloodwork, symptoms, and response monitoring labs.
Most men notice improvements in energy and libido within 2–4 weeks. Muscle mass improvements and body composition changes become noticeable at 8–12 weeks. Full benefits are typically realized by 3–6 months of consistent therapy. Regular labs (every 3–6 months) monitor testosterone levels, hematocrit, estradiol, PSA, and lipids to ensure safety and proper dosing. All five clinics listed above require bloodwork before prescribing.