In-Depth Review • Updated April 2026

MadeMed Review 2026 — Sermorelin, NAD+ & GLP-1 at Direct-to-Patient Pricing

MadeMed offers oral and injectable Sermorelin starting at $99/month, NAD+ therapy, and GLP-1 weight loss — with a Club membership model that removes middlemen to bring costs closer to actual pharmacy pricing.

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Overall Rating

7.8 / 10

Starting Price

$99 / month (oral Sermorelin)

Club Membership

$199 / month (direct-to-patient pricing)

Verdict

Best for oral peptide access at competitive pricing

What is MadeMed?

MadeMed is a telehealth platform delivering physician-prescribed peptide therapy, NAD+ treatment, and GLP-1 weight loss medications directly to patients across the United States. The company is LegitScript certified — an independent healthcare compliance verification standard used by Google, Facebook, and Visa to vet medical providers — which meaningfully sets them apart from unregulated corners of the online supplement and peptide market.

One of MadeMed's most notable features is their delivery format flexibility. Where most telehealth platforms offer only injectables, MadeMed provides both injectable and oral options for Sermorelin, Semaglutide, and Tirzepatide. Oral peptide and GLP-1 options lower the barrier for patients who are needle-averse or newer to compounded therapies.

Their core pricing philosophy, embodied in the MadeMed Club, is to eliminate middlemen and pass pharmacy-level pricing directly to patients. Instead of standard retail markups layered on top of compounding costs, Club members pay a rate closer to what the pharmacy actually charges.

Treatments Offered by MadeMed

Sermorelin — Injectable & Oral

Injectable Sermorelin (9mg/3mL, 30-day) Oral Sermorelin

Sermorelin is a growth hormone releasing hormone (GHRH) analogue that stimulates the pituitary gland to produce more natural growth hormone. MadeMed offers it in both injectable form (9mg/3mL vial, 30-day supply, from $129/month with a required lab test) and as an oral formulation (from $99/month). The oral Sermorelin option is a differentiator — most clinics prescribe injectable only, and the lower price point and needle-free delivery make it more accessible for new patients or those testing the waters before committing to injections.

Lab testing is required for the injectable Sermorelin protocol to establish a baseline before treatment begins.

NAD+ Therapy

Injectable NAD+ NAD+ Nasal Spray

MadeMed offers NAD+ in two delivery formats: subcutaneous injection and nasal spray. The nasal spray is an uncommon offering in telehealth — it provides faster absorption than oral supplementation while avoiding the discomfort of injections. Both formats are available through the platform with physician oversight. Confirm current NAD+ pricing at mademed.com/nad-therapy.

GLP-1 Weight Loss — Injectable & Oral

Injectable Semaglutide Oral Semaglutide Injectable Tirzepatide Oral Tirzepatide

MadeMed offers all four GLP-1 weight loss formats: injectable and oral Semaglutide (GLP-1), and injectable and oral Tirzepatide (GLP-1/GIP dual agonist). The oral GLP-1 options are particularly notable — oral Semaglutide (branded as Rybelsus) typically commands premium pricing, but MadeMed's direct-to-patient model aims to make these accessible at closer-to-pharmacy rates. Confirm current GLP-1 pricing at mademed.com/treatments.

Sexual Health

Tadalafil (ED)

MadeMed Pricing

MadeMed Protocol Pricing (2026)

Oral Sermorelin — monthly from $99 / month
Injectable Sermorelin (9mg/3mL, 30-day) — lab required from $129 / month
NAD+ (injectable & nasal spray) See mademed.com/nad-therapy
Semaglutide / Tirzepatide (injectable & oral) See mademed.com/treatments
MadeMed Club membership $199 / month

The MadeMed Club — Direct-to-Patient Pricing

The MadeMed Club is a $199/month membership that removes the standard retail markup from your medication costs. Rather than paying the inflated prices that typically result from clinic overhead and distributor margins, Club members pay a price closer to what pharmacies actually charge for the compounded medications. For patients running multiple protocols or expecting ongoing therapy, the Club model can significantly reduce the per-treatment cost compared to standard out-of-pocket pricing at other telehealth clinics.

How MadeMed Works

MadeMed operates as a direct-to-patient telehealth platform. After completing an online intake form, patients are connected with a licensed physician who reviews their health history and recommends an appropriate protocol. For injectable Sermorelin, a lab test is required before the prescription is issued. Other protocols may have different intake requirements — confirm during onboarding.

Prescriptions are fulfilled through licensed compounding pharmacies and shipped directly to the patient's door. MadeMed emphasizes discreet, on-time delivery, which is consistently highlighted in patient reviews as a strength. Their online portal handles refills, messaging, and ongoing care coordination.

Who MadeMed is Best For

Who Should Look Elsewhere

Pros

  • Oral Sermorelin from $99/month — one of the lowest price points available
  • Injectable AND oral options for Sermorelin, Semaglutide, and Tirzepatide
  • NAD+ nasal spray — uncommon delivery format
  • MadeMed Club strips out middleman markups at $199/month
  • LegitScript certified — independently verified compliance
  • Consistently praised for fast, discreet delivery
  • Positive patient reviews for product effectiveness and customer service

Cons

  • No confirmed BPC-157, TB-500, PT-141, or TRT
  • GLP-1 and NAD+ pricing not publicly listed — requires inquiry
  • Lab test required for injectable Sermorelin
  • State availability varies — not all states served
  • Narrower formulary than full-service clinics like Marek Health

Patient Reviews of MadeMed

Patient feedback on MadeMed is overwhelmingly positive. Reviewers consistently highlight the effectiveness and quality of the products, noting significant improvements in their goals — whether growth hormone support via Sermorelin or weight loss via GLP-1 programs. The service receives strong marks for being fast, reliable, and easy to use, with particular praise for discreet, on-time delivery.

Customer service is frequently described as responsive and helpful, with a smooth refill process that patients appreciate for ongoing treatment management.

Recurring positive themes:

A smaller number of patients noted difficulties with communication, concerns about recurring charges, or found that a particular medication wasn't the right fit for them — experiences that are common across any large telehealth platform.

MadeMed vs Competitors

vs PeterMD: PeterMD has a broader catalog (TRT, Metformin, Rapamycin, ED) and lower TRT pricing, but MadeMed offers oral peptide and GLP-1 options that PeterMD doesn't. MadeMed wins on delivery format variety; PeterMD wins on breadth.

vs MyRNK: MyRNK includes a free health coach and covers NAD+ and Enclomiphene. MadeMed's Club model may offer better per-unit pricing for high-volume users. MyRNK wins on coaching; MadeMed wins on oral delivery options.

vs Marek Health: Marek Health has a far deeper peptide and hormone catalog with 80+ biomarker diagnostics. MadeMed is more accessible and affordable for patients focused on Sermorelin or GLP-1 specifically. Choose Marek for depth, MadeMed for targeted simplicity.

For comparisons: MadeMed vs PeterMD and MadeMed vs MyRNK.

Our Verdict on MadeMed

MadeMed carves out a genuine niche with its dual delivery formats and direct-to-patient Club pricing model. Oral Sermorelin at $99/month is one of the most accessible entry points for growth hormone support in supervised telehealth, and the NAD+ nasal spray is an unusual option that many competitors simply don't provide. LegitScript certification gives it credibility that unverified online sources can't match.

The narrower formulary — no confirmed TRT, BPC-157, or repair peptides — means it's not the right fit for patients who need a full-spectrum hormone and peptide clinic. But for users focused on Sermorelin, NAD+, or GLP-1 weight loss, MadeMed delivers solid value at a competitive price, especially for Club members running multiple protocols.

Rating: 7.8/10 — Best for Oral Peptide Access & Direct-to-Patient Pricing

Ready to Try MadeMed?

Access oral and injectable Sermorelin, NAD+ therapy, and GLP-1 weight loss at direct-to-patient pricing through the MadeMed Club.

Visit MadeMed →

Frequently asked questions about MadeMed

How much does MadeMed cost?

Oral Sermorelin starts at $99/month. Injectable Sermorelin (9mg/3mL, 30-day supply) starts at $129/month and requires a lab test. The MadeMed Club membership is $199/month and provides direct-to-patient pricing across all protocols. NAD+ and GLP-1 pricing varies — visit mademed.com/nad-therapy and mademed.com/treatments for current rates.

What does MadeMed treat?

MadeMed offers Sermorelin (both injectable and oral) for growth hormone support, NAD+ therapy (injectable and nasal spray) for cellular energy and longevity, GLP-1 weight loss (injectable and oral Semaglutide and Tirzepatide), and Tadalafil for ED.

Does MadeMed require labs?

A lab test is required for injectable Sermorelin before starting treatment. Requirements for other protocols may vary — confirm with MadeMed during your intake consultation.

What is the MadeMed Club?

The MadeMed Club is a $199/month membership that gives patients direct-to-patient pricing — removing distributor and clinic markups so you pay closer to actual pharmacy cost. It's best suited for patients running multiple ongoing protocols who want the lowest available per-treatment pricing.

Is MadeMed legitimate?

Yes. MadeMed is LegitScript certified — an independent compliance verification used by Google, Facebook, and Visa to vet medical providers. They operate as a US-focused telehealth platform prescribing through licensed physicians and compounding pharmacies.

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Medical disclaimer: PeptideRank provides information only. We are not medical providers. Consult a licensed physician before starting any peptide, hormone, or weight loss therapy. Results vary by individual.