Defy Medical is the choice for comprehensive peptide therapy with physician oversight and a wide formulary. MyRNK is the better fit for affordable NAD+ and Sermorelin with a bundled health coach and no lab requirement. They serve different goals — pick based on what you actually need.
| Defy Medical | MyRNK | |
|---|---|---|
| Monthly Cost | ~$200/mo+ (not published) | $129+/mo (published) Clear |
| Labs Required? | Yes | No — labs not required |
| Est. Lab Cost | $100–$300/yr | $0 |
| Consult Type | Video (1-hour physician) | Async + health coach |
| Health Coach | No | Yes — included free |
| NAD+ | Yes (~$180–$225/vial) | $129/mo compounded |
| Sermorelin | Yes (physician supervised) | $129/mo |
| BPC-157 / TB-500 | Yes | Not offered |
| Tesamorelin / CJC-1295 | Yes | Not offered |
| Enclomiphene / TRT | Yes (TRT) | Enclomiphene $189/mo |
| GLP-1 Weight Loss | Limited | Sema $197/mo, Tirze $297/mo |
| Delivery | Standard (restricted ID/MS) | 48-hr to all 50 states |
| Trustpilot | 4.2/5 (3,700+ reviews) | 4.8/5 (24,000+ reviews) |
| Full Review | Read Review → | Read Review → |
MyRNK publishes all pricing and requires no labs to get started. NAD+ and Sermorelin both start at $129/month — making them among the most affordable compounded versions available from a telehealth platform. There are no lab fees, no hidden consult charges, and plans are month-to-month with no contracts.
Defy Medical doesn't publish pricing. Their peptide vials run approximately $180–$225 each, and labs add $100–$300/yr on top. For users who want NAD+ or Sermorelin specifically, MyRNK offers a meaningfully better price with comparable or better access.
Not published. ~$200/mo med cost. Labs required at $100–$300/yr. Consult fee not included. Variable total spend.
NAD+ and Sermorelin $129/mo each. No labs required. $0 lab cost. Month-to-month. Health coach included.
If your protocol calls for BPC-157, TB-500, Tesamorelin, or any of the more specialized peptides, Defy Medical is the only option between the two. Their formulary includes AOD-9604, CJC-1295/Ipamorelin, Epithalon, GHK-Cu, IGF-1 LR3, Kisspeptin, and MOTS-C alongside the core growth hormone peptides.
MyRNK offers Sermorelin and NAD+ — strong protocols, but a limited peptide menu. For users whose goal is NAD+ therapy or growth hormone support via Sermorelin, MyRNK is excellent value. For users who need a broader peptide protocol, Defy Medical is the answer.
These clinics aren't in direct competition — they target different users. If you want comprehensive peptide therapy with full physician oversight, Defy Medical is the right choice.
If your goal is affordable NAD+ therapy, Sermorelin, or Enclomiphene with no lab requirement and a bundled health coach, MyRNK delivers more value for significantly less money.
Defy Medical for traditional peptide therapy — they carry 11+ peptides including BPC-157, TB-500, Tesamorelin, CJC-1295, and more. MyRNK only offers Sermorelin and NAD+.
MyRNK is significantly cheaper. NAD+ and Sermorelin start at $129/month with no lab requirement. Defy Medical's total costs typically exceed $200/month plus $100–$300/yr in labs.
Yes — every MyRNK plan includes a personal health coach at no additional cost, providing diet guidance, lifestyle support, and protocol tracking alongside your physician.
Yes, Defy Medical does offer NAD+ as part of their formulary. However, pricing is not published and the cost is likely higher than MyRNK's $129/month compounded NAD+ program.