Defy Medical wins for users who need a wide peptide formulary with full physician oversight. MadeMed wins for affordable Sermorelin (including oral format), NAD+ in multiple delivery forms, and no lab requirements.
| Defy Medical | MadeMed | |
|---|---|---|
| Monthly Cost | ~$200/mo+ (not published) | $99–$199/mo (published) Clear |
| Labs Required? | Yes | No (most protocols) |
| Est. Lab Cost | $100–$300/yr | $0 |
| Oral Sermorelin | Not offered | $99/mo |
| Injectable Sermorelin | Yes (physician supervised) | $129/mo |
| NAD+ Formats | Injectable | Injectable + nasal spray |
| BPC-157 | Yes | Not offered |
| TB-500 / Tesamorelin | Yes | Not offered |
| CJC-1295 / Ipamorelin | Yes | Not offered |
| GLP-1 (oral option) | Limited | Injectable + oral Sema & Tirze |
| Club Membership | No | $199/mo (direct pricing) |
| LegitScript Certified | No | Yes |
| Founded | 2016 — Dr. Justin Saya | Newer platform |
| Full Review | Read Review → | Read Review → |
MadeMed is one of the few telehealth clinics offering oral Sermorelin at $99/month — making growth hormone support accessible without injections and without a lab requirement. Their injectable Sermorelin is also competitively priced at $129/month. For users who are new to peptide therapy or prefer needle-free delivery, MadeMed has a genuine edge here.
Defy Medical offers physician-supervised injectable Sermorelin within a comprehensive protocol framework, but at higher unpublished cost. For users who want clinically optimized dosing with direct physician input, Defy remains the stronger clinical option.
MadeMed does not offer BPC-157, TB-500, Tesamorelin, CJC-1295, or any of the advanced peptides. Their formulary is purposely narrow: Sermorelin, NAD+, GLP-1, and Tadalafil. If your protocol requires anything beyond that short list, Defy Medical is your clinic.
For users who need advanced peptide protocols, Defy Medical is the only choice between the two — MadeMed simply doesn't carry the formulary.
For users who want affordable, accessible Sermorelin or NAD+ with no lab barriers, MadeMed delivers strong value. Their oral Sermorelin at $99/month and dual-format NAD+ are genuine differentiators in the telehealth market.
MadeMed for cost and format flexibility: oral at $99/mo, injectable at $129/mo, no labs required. Defy Medical for full physician-supervised protocol management.
A $199/month membership providing direct-to-patient pricing across all MadeMed protocols, removing middleman markups so you pay closer to actual pharmacy cost.
No. MadeMed's formulary covers Sermorelin, NAD+, and GLP-1 only. For BPC-157, TB-500, Tesamorelin, or CJC-1295, Defy Medical is the better clinic.